Have you been fortunate enough to recall playing with your great-grandparents? If not, you must have seen their photographs. You must have come across one thing, that they appeared much older as compared to the elders of today. Things are quite different now. You all try to make your aging years as healthy and enjoyable as possible. However, at the time, you couldn’t get away from it. Fortunately, the good news is that the medical sciences have discovered a natural substance that can help you attain a greater quality of fitness and health as you age. You can have a prospect of a longer life by taking ketoglutarate supplements.
Alpha-ketoglutarate is the nitrogen-less part of the amino acids called glutamic acid and glutamine. It is formed in the energy-producing process in most body cells known as the Krebs cycle. Therefore, Alpha-ketoglutarate is used during the healing from injuries, other wounds, and growth. Besides, it is significantly useful in the healing of muscle tissue. In addition, studies have shown that intravenous alpha-ketoglutarate prevents the decline in muscle protein synthesis from recovering from the surgery.
Considering the reasons, it is speculated that oral alpha-ketoglutarate supplements might help in improving muscle mass or strength. Most importantly, research also shows that alpha-ketoglutarate can positively affect aging. It has a tendency to extend the lifespan by inhibiting ATP synthase and the target of rapamycin, as studied in C.elegans.
Alpha-ketoglutarate facilitates cell renewal and restores cellular energy, thereby inhibiting the advancement of frailty and age-related illness. Moreover, it protects from many negative aspects of aging. Most of them are caused due to inflammation related to age and bone mineral density loss. Besides, it also gives protection to the patients undergoing heart surgery as it reduces metabolic abnormalities and provides improved myocardial protection.
In addition, it is possible to obtain alpha-ketoglutarate with several other different compounds, including ornithine and arginine. But it is vital to take note that calcium-AKG offer proven health benefits. By adding this to your routine, you can enhance the rejuvenating benefits naturally derived from the substance during your life.
Everything has a side effect, so do alpha-ketoglutarate supplements as well. However, AKG has been considered quite safe and well-tolerated. Studies investigating the ill effects of alpha-ketoglutarate revealed only some adverse symptoms after continuous use for three years.
Alpha-ketoglutaric acid is comprised of non-essential AA (amino acids). So it is not a substance that doesn’t carry the risk of getting overdosed. Traces of excess alpha-ketoglutarate in the body get degenerated into essential acids for other uses as these are the building blocks. They get excreted from the body in urine.
As such, there is not much known whether ketoglutarate supplements are safe for pregnant women, children, and nursing mothers. Also, it includes children having rare metabolism disorders, in which its levels are enhanced abnormally. Therefore, it is advised to stay away from these compounds to be on the safer side. To make sure they are quality and safe, you must use alpha-ketoglutarate supplements with proper brand names only.